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1

Quality of life analysis in patients with KRAS wild-type metastatic colorectal cancer treated first-line with cetuximab plus irinotecan, fluorouracil and leucovorin

Láng, István, Köhne, Claus-Henning, Folprecht, Gunnar, Rougier, Philippe, Curran, Desmond, Hitre, Erika, Sartorius, Ute, Griebsch, Ingolf, Van Cutsem, Eric

Journal:

European Journal of Cancer

Year:

2013

Language:

english

File:

PDF, 325 KB

english, 2013

2

Cetuximab and Chemotherapy as Initial Treatment for Metastatic Colorectal Cancer

Van Cutsem, Eric, Köhne, Claus-Henning, Hitre, Erika, Zaluski, Jerzy, Chang Chien, Chung-Rong, Makhson, Anatoly, D'Haens, Geert, Pintér, Tamás, Lim, Robert, Bodoky, György, Roh, Jae Kyung, Folprecht,

Journal:

Boston Medical and Surgical Journal

Year:

2009

Language:

english

File:

PDF, 388 KB

english, 2009

3

Survival outcomes in patients with RAS wild-type metastatic colorectal cancer classified by Köhne prognostic category and BRAF mutation status

Siena, Salvatore, Rivera, Fernando, Taieb, Julien, Peeters, Marc, Prenen, Hans, Koukakis, Reija, Demonty, Gaston, Köhne, Claus-Henning

Journal:

Clinical Colorectal Cancer

Year:

2017

Language:

english

File:

PDF, 8.89 MB

english, 2017

4

Induction of cellular immune responses against carcinoembryonic antigen in patients with metastatic tumors after vaccination with altered peptide ligand-loaded dendritic cells

Jana Babatz, Christoph Röllig, Bärbel Löbel, Gunnar Folprecht, Michael Haack, Heinrich Günther, Claus-Henning Köhne, Gerhard Ehninger, Marc Schmitz, Martin Bornhäuser

Journal:

Cancer Immunology, Immunotherapy

Year:

2006

Language:

english

File:

PDF, 279 KB

english, 2006

5

Pharmacokinetics of gemcitabine in a patient with end-stage renal disease: effective clearance of its main metabolite by standard hemodialysis treatment

Alexander Kiani, Claus-Henning Köhne, Thorsten Franz, Jens Passauer, Thorsten Haufe, Peter Gross, Gerhard Ehninger, Eberhard Schleyer

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2003

Language:

english

File:

PDF, 206 KB

english, 2003

6

Relevance of neoadjuvant and adjuvant treatment for patients with resectable liver metastases of colorectal carcinoma

M. Lorenz, Hans-Helge Müller, Elsbeth Staib-Sebler, Gregor Vetter, Christiane Gog, Henrik Petrowsky, Claus-Henning Köhne

Journal:

Langenbeck's Archives of Surgery

Year:

1999

Language:

english

File:

PDF, 77 KB

english, 1999

7

First-line panitumumab plus irinotecan/5-fluorouracil/leucovorin treatment in patients with metastatic colorectal cancer

Claus-Henning Köhne, Ralf Hofheinz, Laurent Mineur, Henry Letocha, Richard Greil, Josef Thaler, Eva Fernebro, Erick Gamelin, Lucy DeCosta, Meinolf Karthaus

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2012

Language:

english

File:

PDF, 584 KB

english, 2012

8

The apoptosis promoting Bcl-2 homologues Bak and Nbk/Bik overcome drug resistance in Mdr-1-negative and Mdr-1-overexpressing breast cancer cell lines

Radetzki, Silke, Köhne, Claus-Henning, von Haefen, Clarissa, Gillissen, Bernhard, Sturm, Isrid, Dörken, Bernd, Daniel, Peter T

Journal:

Year:

2002

Language:

english

File:

PDF, 302 KB

english, 2002

9

Cost-Effectiveness of Targeted Therapy With Cetuximab in Patients With K-ras Wild-Type Colorectal Cancer Presenting With Initially Unresectable Metastases Limited to the Liver in a German Setting

Christian Asseburg, Martin Frank, Claus-Henning Köhne, Jörg Thomas Hartmann, Ingolf Griebsch, Andrea Mohr, Ulrike Osowski, Jeltje Schulten, Thomas Mittendorf

Journal:

Clinical Therapeutics

Year:

2011

Language:

english

File:

PDF, 878 KB

english, 2011

10

Role of new agents in the treatment of colorectal cancer

Claus-Henning Köhne, Caroline Bruce, Gunnar Folprecht, Riccardo Audisio

Journal:

Surgical Oncology

Year:

2004

Language:

english

File:

PDF, 220 KB

english, 2004

11

Matrix-comparative genomic hybridization from multicenter formalin-fixed paraffin-embedded colorectal cancer tissue blocks

Heiko Fensterer, Bernhard Radlwimmer, Jörn Sträter, Malte Buchholz, Daniela E Aust, Catherine Julié, François Radvanyi, Bernard Nordlinger, Claudio Belluco, Eric Van Cutsem, Claus-Henning Köhne, Hans

Journal:

Year:

2007

Language:

english

File:

PDF, 694 KB

english, 2007

12

Panitumumab in Combination With Cytotoxic Chemotherapy for the Treatment of Metastatic Colorectal Carcinoma

Marc Peeters, Allen Cohn, Claus-Henning Köhne, Jean-Yves Douillard

Journal:

Clinical Colorectal Cancer

Year:

2012

Language:

english

File:

PDF, 891 KB

english, 2012

13

Does a patient’s self-reported health-related quality of life predict survival beyond key biomedical data in advanced colorectal cancer?

Fabio Efficace, Andrew Bottomley, Corneel Coens, Kristel Van Steen, Thierry Conroy, Patrick Schöffski, Hans Schmoll, Eric Van Cutsem, Claus-Henning Köhne

Journal:

European Journal of Cancer

Year:

2006

Language:

english

File:

PDF, 141 KB

english, 2006

14

Corrigendum to “Does a patient’s self-reported health-related quality of life predict survival beyond key biomedical data in advanced colorectal cancer?” [Eur. J. Cancer 42 (2006) 42–49]

Fabio Efficace, Andrew Bottomley, Corneel Coens, Kristel Van Steen, Thierry Conroy, Patrick Schöffski, Hans Schmoll, Eric Van Cutsem, Claus-Henning Köhne

Journal:

European Journal of Cancer

Year:

2007

Language:

english

File:

PDF, 95 KB

english, 2007

15

Towards a pan-European consensus on the treatment of patients with colorectal liver metastases

Eric Van Cutsem, Bernard Nordlinger, Rene Adam, Claus-Henning Köhne, Carmelo Pozzo, Graeme Poston, Marc Ychou, Philippe Rougier

Journal:

European Journal of Cancer

Year:

2006

Language:

english

File:

PDF, 229 KB

english, 2006

16

Does chemotherapy prior to liver resection increase the potential for cure in patients with metastatic colorectal cancer? A report from the European Colorectal Metastases Treatment Group

Bernard Nordlinger, Eric Van Cutsem, Philippe Rougier, Claus-Henning Köhne, Marc Ychou, Alberto Sobrero, Rene Adam, Dag Arvidsson, Alfredo Carrato, Vassilis Georgoulias, Felice Giuliante, Bengt Glimel

Journal:

European Journal of Cancer

Year:

2007

Language:

english

File:

PDF, 246 KB

english, 2007

17

Expert opinion on management of gastric and gastro-oesophageal junction adenocarcinoma on behalf of the European Organisation for Research and Treatment of Cancer (EORTC) - gastrointestinal cancer group

Eric Van Cutsem, Cornelius Van de Velde, Arnaud Roth, Florian Lordick, Claus-Henning Köhne, Stefano Cascinu, Matti Aapro

Journal:

European Journal of Cancer

Year:

2008

Language:

english

File:

PDF, 232 KB

english, 2008

18

Addition of cetuximab to chemotherapy as first-line treatment for KRAS wild-type metastatic colorectal cancer: Pooled analysis of the CRYSTAL and OPUS randomised clinical trials

Carsten Bokemeyer, Eric Van Cutsem, Philippe Rougier, Fortunato Ciardiello, Steffen Heeger, Michael Schlichting, Ilhan Celik, Claus-Henning Köhne

Journal:

European Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 504 KB

english, 2012

19

Clinical predictive factors

Claus-Henning Köhne, Udo Vanhoefer, Gernot Hartung

Journal:

European Journal of Cancer

Year:

2009

Language:

english

File:

PDF, 90 KB

english, 2009

20

Should adjuvant chemotherapy become standard treatment for patients with stage II colon cancer?

Alberto Sobrero, Claus-Henning Köhne

Journal:

The Lancet Oncology

Year:

2006

Language:

english

File:

PDF, 61 KB

english, 2006

21

Cetuximab in metastatic colorectal cancer – Author' reply

Gunnar Folprecht, Claus-Henning Köhne

Journal:

The Lancet Oncology

Year:

2010

Language:

english

File:

PDF, 42 KB

english, 2010

22

The gefitinib long-term responder (LTR)—A cancer stem-like cell story? Insights from molecular analyses of German long-term responders treated in the IRESSA expanded access program (EAP)

Gottschling, Sandra, Herpel, Esther, Eberhardt, Wilfried E.E., Heigener, David F., Fischer, Jürgen R., Köhne, Claus-Henning, Kortsik, Cornelius, Kuhnt, Thomas, Muley, Thomas, Meister, Michael, Bischof

Journal:

Year:

2012

Language:

english

File:

PDF, 1.15 MB

english, 2012

23

Skin toxicity and quality of life in patients with metastatic colorectal cancer during first-line panitumumab plus FOLFIRI treatment in a single-arm phase II study

Josef Thaler, Meinolf Karthaus, Laurent Mineur, Richard Greil, Henry Letocha, Ralf Hofheinz, Eva Fernebro, Erick Gamelin, Ana Baños, Claus-Henning Köhne

Journal:

Year:

2012

Language:

english

File:

PDF, 226 KB

english, 2012

24

A randomised phase III intergroup trial comparing high-dose infusional 5-fluorouracil with or without folinic acid with standard bolus 5-fluorouracil/folinic acid in the adjuvant treatment of stage III colon cancer: The Pan-European Trial in Adjuvant Colon Cancer 2 study

Köhne, Claus-Henning, Bedenne, Laurent, Carrato, Alfredo, Bouché, Olivier, Popov, Ivan, Gaspà, Losa, Valladares, Manuel, Rougier, Phillipe, Gog, Christiane, Reichardt, Peter, Wils, Jacques, Pignatti,

Journal:

European Journal of Cancer

Year:

2013

Language:

english

File:

PDF, 373 KB

english, 2013

25

Modulation of cytotoxic drug activity by dipyridamole

Schmoll, Hans-Joachim, Harstrick, Andreas, Köhne-Wömpner, Claus-Henning, Schöber, Christoph, Wilke, Hansjochen, Poliwoda, Hubert

Journal:

Cancer Treatment Reviews

Year:

1990

Language:

english

File:

PDF, 722 KB

english, 1990

26

Drug Insight: metastatic colorectal cancer—oral fluoropyrimidines and new perspectives in the adjuvant setting

Folprecht, Gunnar, Köhne, Claus-Henning

Journal:

Nature Clinical Practice Oncology

Year:

2005

Language:

english

File:

PDF, 168 KB

english, 2005

27

Profiles of Activation, Differentiation–Markers, or β-Integrins on T Cells Contribute to Predict T Cells’ Antileukemic Responses After Stimulation With Leukemia-derived Dendritic Cells

Vogt, Valentin, Schick, Julia, Ansprenger, Christian, Braeu, Marion, Kroell, Tanja, Kraemer, Doris, Köhne, Claus-Henning, Hausmann, Andreas, Buhmann, Raymund, Tischer, Johanna, Schmetzer, Helga

Journal:

Journal of Immunotherapy

Year:

2014

Language:

english

File:

PDF, 1.15 MB

english, 2014

28

Antileukemic T-cell Responses Can Be Predicted by the Composition of Specific Regulatory T-cell Subpopulations

Schick, Julia, Vogt, Valentin, Zerwes, Marion, Kroell, Tanja, Kraemer, Doris, Köhne, Claus-Henning, Hausmann, Andreas, Buhmann, Raymund, Tischer, Johanna, Schmetzer, Helga

Journal:

Journla of Immunotherapy

Year:

2013

Language:

english

File:

PDF, 799 KB

english, 2013

29

Toxicity of Irinotecan in Patients with Colorectal Cancer

Van Cutsem, Eric, Douillard, Jean-Yves, Köhne, Claus-Henning

Journal:

Boston Medical and Surgical Journal

Year:

2001

Language:

english

File:

PDF, 144 KB

english, 2001

30

Long-Term Remissions in Metastatic Malignant Melanoma Following Chemotherapy and Tamoxifen Maintenance

Metzner, Bernd, Casper, Jochen, Hartung, Gernot, Rosien, Bernd, Hölzle, Erhard, Pelzer, Peter, Köhne, Claus-Henning

Journal:

Year:

2011

Language:

english

File:

PDF, 128 KB

english, 2011

31

Expression and prognostic value of FAS receptor/FAS ligand and TrailR1/TrailR2 in acute myeloid leukemia

Pordzik, Sandra, Petrovici, Karin, Schmid, Christoph, Kroell, Tanja, Schweiger, Cornelia, Köhne, Claus-Henning, Schmetzer, Helga

Journal:

Hematology (American Society of Hematology)

Year:

2011

Language:

english

File:

PDF, 475 KB

english, 2011

32

Clinical advances with topoisomerase I inhibitors in gastrointestinal malignancies

Armand, Jean-Pierre, Cunningham, David, van Cutsem, Eric, Misset, Jean-Louis, Kohne, Claus-Henning

Journal:

Anti-Cancer Drugs

Year:

1999

File:

PDF, 614 KB

1999

33

P-319Characteristics and response outcomes of long-term survivors in studies of first-line panitumumab for metastatic colorectal cancer

Köhne, Claus-Henning, Peeters, Marc, Carrato, Alfredo, Coriat, Romain, Rivera, Fernando, Koukakis, Reija, Demonty, Gaston, Geissler, Michael

Journal:

Annals of Oncology

Year:

2017

Language:

english

File:

PDF, 434 KB

english, 2017

34

The apoptosis promoting Bcl-2 homologues Bak and Nbk/Bik overcome drug resistance in Mdr-1-negative and Mdr-1-overexpressing breast cancer cell lines

Radetzki, Silke, Köhne, Claus-Henning, von Haefen, Clarissa, Gillissen, Bernhard, Sturm, Isrid, Dörken, Bernd, Daniel, Peter T

Journal:

Year:

2002

Language:

english

File:

PDF, 302 KB

english, 2002

35

Stellenwert der intensivierten Chemotherapie und der neuen Substanzen in der adjuvanten und palliativen Situation beim kolorektalen Karzinom

Köhne, Claus-Henning

Journal:

Chirurgische Gastroenterologie

Year:

2005

File:

PDF, 83 KB

2005

36

Reporting of patient characteristics and stratification factors in phase 3 trials investigating first-line systemic treatment of metastatic colorectal cancer: A systematic review

Goey, Kaitlyn K.H., Mahmoud, Remi, Sørbye, Halfdan, Glimelius, Bengt, Köhne, Claus-Henning, Sargent, Daniel J., Punt, Cornelis J.A., van Oijen, Martijn G.H., Koopman, Miriam

Journal:

European Journal of Cancer

Year:

2018

Language:

english

File:

PDF, 1020 KB

english, 2018

37

Weekly 24-Hour Infusion of High-Dose 5-Fluorouracil plus Folinic Acid in Combination with Mitomycin C for the Treatment of Advanced Gastric Cancer

Kretzschmar, Albrecht, Reichardt, Peter, Thuss-Patience, Peter C., Hohenberger, Peter, Benter, Thomas, Dörken, Bernd, Köhne, Claus-Henning

Journal:

Year:

2000

Language:

english

File:

PDF, 227 KB

english, 2000

38

The changing face of treatment for metastatic colorectal cancer

Pfeiffer, Per, Köhne, Claus-Henning, Qvortrup, Camilla

Journal:

Expert Review of Anticancer Therapy

Year:

2018

Language:

english

File:

PDF, 937 KB

english, 2018

39

Vinflunine in the treatment of advanced urothelial cancer: clinical evidence and experience

Gerullis, Holger, Wawroschek, Friedhelm, Köhne, Claus-Henning, Ecke, Thorsten Holger

Journal:

Therapeutic Advances in Urology

Year:

2017

Language:

english

File:

PDF, 78 KB

english, 2017

40

Relevance of tumour-infiltrating lymphocytes, PD-1 and PD-L1 in patients with high-risk, nodal-metastasised breast cancer of the German Adjuvant Intergroup Node–positive study

Noske, Aurelia, Möbus, Volker, Weber, Karsten, Schmatloch, Sabine, Weichert, Wilko, Köhne, Claus-Henning, Solbach, Christine, Ingold Heppner, Barbara, Steiger, Katja, Müller, Volkmar, Fasching, Peter,

Journal:

European Journal of Cancer

Year:

2019

File:

PDF, 2.16 MB

2019

41

Impact of Primary Tumour Location and Early Tumour Shrinkage on Outcomes in Patients with RAS Wild-Type Metastatic Colorectal Cancer Following First-Line FOLFIRI Plus Panitumumab

Köhne, Claus-Henning, Karthaus, Meinolf, Mineur, Laurent, Thaler, Josef, Van den Eynde, Marc, Gallego, Javier, Koukakis, Reija, Berkhout, Marloes, Hofheinz, Ralf-Dieter

Journal:

Year:

2019

Language:

english

File:

PDF, 821 KB

english, 2019

42

Stellenwert der neoadjuvanten und adjuvanten Chemotherapie bei kolorektalen Lebermetastasen

Köhne, Claus-Henning, Schumann-Binarsch, Silke

Journal:

Viszeralmedizin

Year:

2012

File:

PDF, 126 KB

2012